Showing posts with label Polysorbate 80. Show all posts
Showing posts with label Polysorbate 80. Show all posts

18.1.12

Can supplements worsen Crohn's symptoms?

"Hidden hazards of vitamin and mineral tablets" by Zoltan Rona
"Other potentially harmful additives:  sodium benzoate, bht, bha, tartrazine, lactose, peanut oil, hydrogenated cottonseed oil, titanium dioxide, polysorbate 80, microcrystalline cellulose, magnesium stearate, red dye no. 33 and 40, ethyl cellulose, sorbic acid, fractionated coconut oil and cornstarch."

Vitamin Supplements Associated With Increased Risk for Death

See my post Can Polysorbate 80 worsen Crohn's symptoms?

15.6.11

Which food additives are most concerning in Crohn's?

In general:


  • sodium nitrate
  • saccharin (US, not allowed in Canada)
  • caffeine
  • olestra (US, not allowed in Canada), calorie-free fat substitute
  • acesulfame-potassium (also known as acesulfame-K), artifical sweetner
  • artificial colouring
  • salt
  • sugar



  • Especially in Crohn's Disease:
    • polysorbate 80 (nonemolient surfuctant, emulsifier)  [read more at my post here]  It is known to promote translocation of e-coli into ...
    • carrageenan, sulphated polysaccharide used as gelatin (Vegan, Vegetarian diets), thickner, stabilizer, emulsifier  [read more at my post here]
    Food additives permitted for use in Canada

    Guidelines for the Use of Food Additives and/or Processing Aids Intended for Fresh Fruits and Vegetable

    Food additives: The good and the bug at C-Health

    4.6.11

    Does Polysorbate 80 (emulsifier) worsen Crohn's symptoms?

    "Food Components Influence Bacterial Pathology of Crohn's Disease" from Medscape Today News
    "The translocation of Escherichia coli across M (microfold) cells and Peyer's patches in Crohn's disease is inhibited by plant fiber but increases with low concentrations of polysorbate 80, an emulsifier commonly used in processed foods, new research findings suggest."

    "Translocation of Crohn's disease Escherichia coliacross M-cells: contrasting effects of soluble plant fibres and emulsifiers" in Inflammatory Bowel Disease (2010)
    " We have assessed the effect of soluble non-starch polysaccharide (NSP) and food emulsifiers on translocation of Escherichia coli across M-cells. ... Polysorbate-80, 0.01% vol/vol, increased E coli translocation through Caco2-cl1 monolayers 59-fold (p<0.05) and, at higher concentrations, increased translocation across M-cells. Similarly, E coli translocation across human Peyer's patches was reduced 45±7% by soluble plantain NSP (5 mg/ml) and increased 2-fold by polysorbate-80 (0.1% vol/vol). ...
    Translocation of E coli across M-cells is reduced by soluble plant fibres, particularly plantain and broccoli, but increased by the emulsifier Polysorbate-80. These effects occur at relevant concentrations and may contribute to the impact of dietary factors on Crohn's disease pathogenesis."