Eicosanoids on Wikipedia
"In biochemistry, eicosanoids are signaling molecules made by oxidation of twenty-carbon essential fatty acids, (EFAs). They exert complex control over many bodily systems, mainly in inflammation or immunity, and as messengers in the central nervous system. The networks of controls that depend upon eicosanoids are among the most complex in the human body.
Eicosanoids derive from either omega-3 (?-3) or omega-6 (?-6) EFAs. The ?-6 eicosanoids are generally pro-inflammatory; ?-3's are much less so. The amounts and balance of these fats in a person's diet will affect the body's eicosanoid-controlled functions, with effects on cardiovascular disease, triglycerides, blood pressure, and arthritis. Anti-inflammatory drugs such as aspirin and other NSAIDs act by downregulating eicosanoid synthesis.
There are four families of eicosanoids—the prostaglandins, prostacyclins, the thromboxanes and the leukotrienes. For each, there are two or three separate series, derived either from an ?-3 or ?-6 EFA. These series' different activities largely explain the health effects of ?-3 and ?-6 fats."
"Reducing inflammation with diet: The Story of Eicosanoid Inhibition", Institute for Traditional Medicine (2003)
Showing posts with label omega 6 fatty acids. Show all posts
Showing posts with label omega 6 fatty acids. Show all posts
28.6.11
Do nuts influence Crohn's inflammation?
The effect of nuts on inflammation. [Asia Pac J Clin Nutr. 2008] - PubMed result
Read the full article here.
"In conclusion, nuts are complex food matrices containing diverse nutrients and other chemical constituents that may favourably influence human physiology. These substances may inhibit the activation of the innate immune system, probably by decreasing the production of proinflammatory cytokines such as CRP, IL-6, TNF-α or IL-18, and increase the production of anti-inflammatory cytokines such as adiponectin. This may improve the proinflammatory milieu, which in turn ameliorates endothelial dysfunction at the vascular level, and ultimately decreases the risk of insulin resistance, type 2 diabetes and coronary heart disease. The capacity of nuts to modulate inflammation may explain at least in part why frequent nut consumption is associated with reduced risk of diabetes and cardiovascular disease in epidemiological studies."
Read the full article here.
"In conclusion, nuts are complex food matrices containing diverse nutrients and other chemical constituents that may favourably influence human physiology. These substances may inhibit the activation of the innate immune system, probably by decreasing the production of proinflammatory cytokines such as CRP, IL-6, TNF-α or IL-18, and increase the production of anti-inflammatory cytokines such as adiponectin. This may improve the proinflammatory milieu, which in turn ameliorates endothelial dysfunction at the vascular level, and ultimately decreases the risk of insulin resistance, type 2 diabetes and coronary heart disease. The capacity of nuts to modulate inflammation may explain at least in part why frequent nut consumption is associated with reduced risk of diabetes and cardiovascular disease in epidemiological studies."
How do omega-6 fatty acids influence Crohn's?
Do I need to pay attention to ratios, total amounts or both?
How many grams per day are appropriate?
How many grams per day are appropriate?
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