Showing posts with label immune deficiency. Show all posts
Showing posts with label immune deficiency. Show all posts

14.6.11

What are the secondary effects in CD?

"New insights into the pathogenesis of Crohn's disease: are they relevant for therapeutic options?" in Swiss Med Wkly (2009)
"Data on NOD2/CARD15 expression suggest that macrophages and epithelial cells could be the locus of the primary pathophysiological defect and that T-cell activation might just be a secondary effect inducing chronification of the inflammation, perhaps as backup mechanism to insufficient innate immunity."