"Translocation of Crohn's disease Escherichia coliacross M-cells: contrasting effects of soluble plant fibres and emulsifiers" in Inflammatory Bowel Disease (2010)
" We have assessed the effect of soluble non-starch polysaccharide (NSP) and food emulsifiers on translocation ofEscherichia coli across M-cells. ... Plantain and broccoli NSP markedly reduced E coli translocation across M-cells at 5 mg/ml (range 45.3–82.6% inhibition, p<0.01).... Similarly, E coli translocation across human Peyer's patches was reduced 45±7% by soluble plantain NSP (5 mg/ml). ... Translocation of E coli across M-cells is reduced by soluble plant fibres, particularly plantain and broccoli...."
"Influence of dietary blueberry and broccoli on cecal microbiota activity and colon morphology in mdr1a−/− mice, a model of inflammatory bowel diseases" in Nutrition (2012)
"In comparison to mice fed the control diet, blueberry and broccoli supplementation altered cecum microbiota similarly with the exception of Faecalibacterium prausnitzii, which was found to be significantly lower in broccoli-fed mice. High concentrations of butyric acid and low concentrations of succinic acid were observed in the cecum of broccoli-fed mice. Blueberry- and broccoli-supplemented diets increased colon crypt size and the number of goblet cells per crypt. Only the broccoli-supplemented diet significantly lowered colonic inflammation compared to mice fed the control diet. Translocation of total microbes to mesenteric lymph nodes was lower in broccoli-fed mice compared to blueberry and control diet groups."
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