6.6.11

Are some therapies more suitable to the internal-perforating CD subtype?

Positive serologic tests for internal-perforating CD subtype:
from Inflammatory Bowel Disease:  Translating Basic Science into clinical practice, Targon et al., p. 236-7
  • Anti-cBirl flagellin
    • associated with small bowel disease
  • ASCA
    • IgA and IgG Anti-Saccharomyces cerevisiae antibodies
    • associated with small bowel disease
  • IgA Anti-OmpC
    • antibody against outer membrane porin C Escherichea coli

METHODS OF ASSESSING CROHN'S DISEASE PATIENT PHENOTYPE BY 12 SEROLOGIC RESPONSE, patents, Targen
"...[I]nternal perforating disease is a clinical subtype of Crohn's disease defined by current or previous evidence of entero-enteric or entero-vesicular fistulae, intra-abdominal abscesses, or small bowel perforation."

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