Does pycnogenol reduce Crohn's symptoms?

Proanthocyanidin
"Proanthocyanidin (PA or PAC), also known as procyanidin, oligomeric proanthocyanidin (OPC), leukocyanidin, leucoanthocyanin and condensed tannins, is a class of flavanols. ...

Proanthocyanidins represent a group of condensed flavan-3-ols, such as procyanidins, prodelphinidins and propelargonidins, that can be found in many plants, most notably apples, maritime pine bark, cinnamon, cocoa beans, grape seed, grape skin (procyanidins and prodelphinidins), and red wines of Vitis vinifera (the common grape). However, bilberry, cranberry, black currant, green tea, black tea, and other plants also contain these flavonoids. Cocoa beans contain the highest concentrations . Proanthocyanidins can also be isolated from Quercus petraea and Q. robur heartwood (wine barrel oaks).

Apples contain on average per serving about eight times the amount of proanthocyanidin found in wine, with some of the highest amounts found in the Red Delicious and Granny Smith varieties.

A patented extract of maritime pine bark called Pycnogenol bears 65-75 percent proanthocyanidins (procyanidins). Thus a 100 mg serving would contain 65 to 75 mg of proanthocyanidins (procyanidins).

Proanthocyanidin glycosides can be isolated from cocoa liquor.

The seed testas of field beans (Vicia faba) contain proanthocyanidins that affect the digestibility in piglets and could have an inhibitory activity on enzymes.

Proanthocyanidins have strong anti-oxidant properties. Foods rich in proanthocyanidins have high oxygen radical absorbance capacity which has been linked to numerous health benefits such as weight management, cell health, and cardiovascular health. Scientists continue to research the relevance of proanthocyanidins' strong anti-oxidant properties in vivo for such applications as cancer prevention and cardiovascular health. USDA does maintain a database of proanthocyanidin content and structure for many foods, but dietary supplements proanthocyanidin content has not been well documented."

See Maritime Pine on Wikipedia

Pycnogenol







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