4.6.11

Is a meat diet significant to pathogenesis and relapse in CD?

Meat is a very nutritionally dense food.

Cross-cultural studies of Asian and Western diets suggest that an increase in the consumption of animal meat and fats may be a factor in the pathogensis of CD. 
See "Is there a link between food and intestinal microbes and the occurrence of Crohn's disease and ulcerative colitis?" published in JGHF (2008)
From the Abstract:  We found several papers describing the positive association of animal meat and sweets and sugar with the occurrence of CD and UC.

See also "Epidemiologic analysis of Crohn disease in Japan: increased dietary intake of n-6 polyunsaturated fatty acids and animal protein relates to the increased incidence of Crohn disease in Japan." in Am J Clin Nutrition (1996)

In Japan, studies show that semi-vegetarien diets (i.e., diets with less meat) prevented CD relapse perhaps due to the prebiotic qualities of some plants).
See "Lifestyle-related disease in Crohn’s disease: Relapse prevention by a semi-vegetarian diet" in World J Gastroenterol (2010)
From the Abstract:  SVD was highly effective in preventing relapse in CD.

In Canadian children, studies show that diets with less meat have a weaker association with CD.
See "Dietary patterns and risk for Crohn's disease in children" in Inflamm Bowel Dis (2008) Conclusions:   Findings:  Pattern 2, common to both boys and girls, was characterized by vegetables, fruits, olive oil, fish, grains, and nuts and was inversely associated with CD in both genders (girls: OR 0.3, 95% CI 0.1-0.9; boys: OR 0.2, 95% CI 0.1-0.5).

Some alternative anectodally successful diets for CD are relatively high in meats, including the SCD and paleo diets.

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