Peter Born: "Carbohydrate malabsorption in patients with non-specific abdominal complaints" in World Journal of Gastroenterology (2007) [PDF]
"The clinical symptoms of carbohydrate malabsorption include flatulence, abdominal cramps and pain, diarrhea, and sometimes even headache, usually after the ingestion of a product containing the incompletely absorbed sugar. There are no symptoms specific for a single sugar. An association with reduced plasma levels of tryptophan has been discussed as a possible mechanism for this. ...
However, there are data showing that, in patients (mainly females) with fructose and sorbitol malabsorption, diet can improve not only gastrointestinal disturbances, but also mood.
The gastrointestinal symptoms are thought to be provoked by the increased osmotic load of the
sugar, with an augmented intraluminal volume (water) and a consequent acceleration of intestinal passage. Gas production and diarrhea occur in connection with the bacterial flora in the colon, the unabsorbed sugar presenting as a substrate for increased bacterial fermentation. Moreover, the capacity of the colon to absorb the surplus water plays a role in the pathogenesis of diarrhea."
No comments:
Post a Comment