9.7.11

Does quercetin reduce Crohn's symptoms?

Quercetin on Wikipedia
" ... a plant-derived flavonoid found in fruits, vegetables, leaves and grains."

"Several laboratory studies show quercetin may have anti-inflammatory properties, and it is being investigated for a wide range of potential health benefits. From in vitro studies, quercetin has demonstrated anti-inflammatory activity by inhibiting both synthesis and release of histamine and other allergic/inflammatory mediators. In addition, it may have antioxidant activity and vitamin C-sparing action."

Other names: Sophoretin, Meletin, Quercetine, Xanthaurine, Quercetol, Quercitin, Quertine, Flavin meletin

Flavonoids from Wikipedia

Good sources of flavonoids include all citrus fruits, berries, ginkgo biloba, onions[28][29] (particularly red onion[30]), parsley,[31] pulses,[32] tea (especially white and green tea), red wine, seabuckthorn, anddark chocolate (with a cocoa content of seventy percent or greater).flavonoids, derived from 2-phenylchromen-4-one (2-phenyl-1,4-benzopyrone) structure (examples: quercetin, rutin).

Flavonoids (or bioflavonoids) (from the Latin word flavus meaning yellow), also collectively known as Vitamin P and citrin,[1] are a class of plant secondary metabolites or yellow pigments having a structure similar to that of flavones. According to the IUPAC nomenclature,[2] they can be classified into:
isoflavonoids, derived from 3-phenylchromen-4-one (3-phenyl-1,4-benzopyrone) structure
neoflavonoids, derived from 4-phenylcoumarine (4-phenyl-1,2-benzopyrone) structure.

neoflavonoids, derived from 4-phenylcoumarine (4-phenyl-1,2-benzopyrone) structure.

Good sources of flavonoids include all citrus fruits, berries, ginkgo biloba, onions[28][29] (particularly red onion[30]), parsley,[31] pulses,[32] tea (especially white and green tea), red wine, seabuckthorn, anddark chocolate (with a cocoa content of seventy percent or greater).

"Quercetin Inhibits TNF-Induced NF-?B Transcription Factor Recruitment to Proinflammatory Gene Promoters in Murine Intestinal Epithelial Cells" In American Society for Nutrition (2007)

"These studies support an anti-inflammatory effect of quercetin in epithelial cells through mechanisms that inhibit cofactor recruitment at the chromatin of proinflammatory genes."

"Influence of Quercetin Supplementation on Disease Risk Factors in Community-Dwelling Adults" in Journal of the American Dietetic Association (2011)

"Change in inflammatory measures did not differ between groups except for a slight decrease in interleukin-6 for the Q-1,000 group.

Conclusions
Q-500 or Q-1,000 supplementation for 12 weeks had a negligible influence on disease risk factors."

No comments: